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Total 62 results found since Jan 2013.

Comparison of awareness, attitudes and knowledge on human papilloma virus vaccination in Singapore: 2019 versus 2013
CONCLUSION: The Singapore government's efforts to improve cervical cancer awareness through national campaigns and policy changes have led to an improvement in knowledge of HPV infection. However, this has not translated into improvements in the vaccine acceptance rates. The decision for vaccine uptake is complex, and there are multiple factors to be addressed to ensure cost-effective implementation of the strategies. Our study highlights the need for effective dissemination of vaccine information, additional subsidies and consideration of a mandatory school-based vaccination programme.PMID:37675669 | DOI:10.4103/singaporemedj.SMJ-2020-437
Source: Singapore Medical Journal - September 7, 2023 Category: General Medicine Authors: Michelle E-Jyn Kwek Joella Xiaohong Ang Manisha Mathur Lily Chye Lee Kho Source Type: research

COVID-19 Severity and Waning Immunity After up to 4 mRNA Vaccine Doses in 73  608 Patients With Cancer and 621 475 Matched Controls in Singapore: A Nationwide Cohort Study
CONCLUSION: This cohort study provides evidence of the clinical effectiveness of mRNA-based vaccines against COVID-19 in patients with cancer. Longevity of immunity in preventing severe COVID-19 outcomes in actively treated patients with cancer, cancer survivors, and matched controls was observed at least 5 months after the third or fourth dose.PMID:37440245 | DOI:10.1001/jamaoncol.2023.2271
Source: Cancer Control - July 13, 2023 Category: Cancer & Oncology Authors: Wei Chong Tan Janice Yu Jin Tan Joline Si Jing Lim Ryan Ying Cong Tan Ainsley Ryan Yan Bin Lee Fun Loon Leong Soo Chin Lee Louis Yi Ann Chai Thuan Tong Tan Muhammad Ismail Bin Abdul Malek Benjamin Ong David Chien Lye Calvin J Chiew Wee Joo Chng Soon Thye Source Type: research

Near-atomic architecture of Singapore grouper iridovirus and implications for giant virus assembly
Nat Commun. 2023 Apr 12;14(1):2050. doi: 10.1038/s41467-023-37681-9.ABSTRACTSingapore grouper iridovirus (SGIV), one of the nucleocytoviricota viruses (NCVs), is a highly pathogenic iridovirid. SGIV infection results in massive economic losses to the aquaculture industry and significantly threatens global biodiversity. In recent years, high morbidity and mortality in aquatic animals have been caused by iridovirid infections worldwide. Effective control and prevention strategies are urgently needed. Here, we present a near-atomic architecture of the SGIV capsid and identify eight types of capsid proteins. The viral inner me...
Source: Cancer Control - April 11, 2023 Category: Cancer & Oncology Authors: Zhennan Zhao Youhua Huang Congcong Liu Dongjie Zhu Shuaixin Gao Sheng Liu Ruchao Peng Ya Zhang Xiaohong Huang Jianxun Qi Catherine C L Wong Xinzheng Zhang Peiyi Wang Qiwei Qin George F Gao Source Type: research

What is the optimal country for minimum COVID-19 morbidity and mortality rates?
The objective of this manuscript is to rank world countries based on the anticipated scope of COVID-19 morbidity and mortality, measured in terms of prevalence per 1 million persons, from the lowest to the highest. The ranking of 162 countries is based on predictions of empirical models, which include three explanatory variables: hospital beds per thousand persons, population density, and the median age of the country's population. Referring to the COVID-19 scope of morbidity, the lowest likelihood of infection is obtained in Niger and Mali, where the dominant characteristic is the young median age (15.1-16.4 years). Refer...
Source: Environmental Science and Pollution Research International - March 31, 2023 Category: Environmental Health Authors: Yuval Arbel Yifat Arbel Amichai Kerner Miryam Kerner Source Type: research

Impact of including boys in the national school-based human papillomavirus vaccination programme in Singapore: A modelling-based cost-effectiveness analysis
Vaccine. 2023 Feb 14:S0264-410X(23)00160-3. doi: 10.1016/j.vaccine.2023.02.025. Online ahead of print.ABSTRACTGlobally, gender-neutral Human Papillomavirus (HPV) vaccination programmes are gaining traction. Although cervical cancer remains the most prevalent, other HPV-related cancers are increasingly recognised as important, especially among men who have sex with men. We assessed if including adolescent boys in Singapore's school-based HPV vaccination programme is cost-effective from the healthcare perspective. We adapted a World Health Organization-supported model, Papillomavirus Rapid Interface for Modelling and Economi...
Source: Vaccine - February 16, 2023 Category: Allergy & Immunology Authors: Muhammad Taufeeq Wahab Rayner Kay Jin Tan Alex R Cook Kiesha Prem Source Type: research